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research How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges

May 2024 in “International Journal of Nanomedicine”

This review examined the diverse therapeutic potentials of cannabinoids, highlighting their applications in pain, neurological, and cancer treatments, and emphasized the benefits of biodegradable polymers in improving drug delivery; however, further clinical trials are needed to fully explore these potentials.

research Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice

28 citations , September 2019 in “International Journal of Nanomedicine”

This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.

research Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy

47 citations , December 2019 in “Biomaterials”

This study demonstrated effective delivery of CRISPR/Cas9 components to dermal papilla cells in androgenic alopecia animals using ultrasound-activated nanoparticles, resulting in specific gene editing and hair growth recovery.

research Nano drug delivery systems: a promising approach to scar prevention and treatment

15 citations , August 2023 in “Journal of Nanobiotechnology”

This review highlights recent advancements in using nanotechnology for scar prevention and treatment, emphasizing the unique properties of nanomaterials in drug delivery and the challenges that remain in maximizing their potential for effective scar interventions.

research Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles

161 citations , April 2006 in “Journal of Investigative Dermatology”

Liposomes with certain properties can effectively deliver drugs deep into hair follicles.

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community How come topical fin doesn't deliver superior results when it suppresses scalp DHT more effectively than oral?

in Finasteride/Dutasteride 36 upvotes 1 year ago

Topical finasteride is believed to reduce scalp DHT more than oral forms, but its effectiveness is questioned due to inconsistent application and absorption. Oral finasteride is considered more effective because it consistently reduces systemic DHT, ensuring more reliable results.

community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

15 upvotes 6 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

community Fin/Dut + Min or Shave it off and get used to being bald, Hair System is a non-option.

16 upvotes 1 week ago

Hair systems can be effective but may cause anxiety and maintenance issues, while some prefer medications like finasteride and minoxidil despite potential side effects. Ultimately, personal confidence and character are more important than hair appearance.

community Has Anyone Heard About Ethossomal Finasteride? 6x Finasteride Delivery in Hair Folicule?

36 upvotes 3 years ago

A user is considering switching from oral to topical finasteride to reduce systemic DHT impact and is exploring ethossomal finasteride for better skin penetration and potential hair regrowth. They found ethossomal finasteride in Brazil and are seeking opinions on its effectiveness compared to other topical delivery methods.

community Napkin math: are we using 100x more topical finasteride than necessary?

in Finasteride/Dutasteride 4 upvotes 5 months ago

Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.

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