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    Glossary Eczema Area and Severity Index

    tool measuring eczema extent and severity across body regions

    The Eczema Area and Severity Index (EASI) is a tool used by healthcare professionals to measure the extent and severity of eczema, also known as atopic dermatitis. It assesses four body regions (head/neck, trunk, upper limbs, and lower limbs) for redness, thickness, scratching, and lichenification (skin thickening), providing a score that helps guide treatment decisions and monitor disease progression.

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    1. 170 Forecasting Phase 3 Dose-Response for Abrocitinib, an Oral Janus Kinase 1 Selective Inhibitor, Using Investigator’s Global Assessment and Eczema Area and Severity Index Journal of Investigative Dermatology · 2019
    2. Oral tofacitinib: a promising treatment in atopic dermatitis, alopecia areata and vitiligo Clinical and Experimental Dermatology · 2017 · 37 citations
    3. Tralokinumab Treatment in Adult Atopic Dermatitis Patients: 28‐Week Evaluation of Clinical Effectiveness, Safety, Serum Proteins and Total IgE Levels Allergy · 2024 · 10 citations
    4. Allergen‐specific immunotherapy improves alopecia totalis in a severe atopic dermatitis patient The Journal of Dermatology · 2023 · 1 citations
    5. Nemolizumab Treatment for Severe Atopic Dermatitis Led to the Simultaneous Improvement of Coexisting Refractory Alopecia Areata: A Case Report The Journal of Dermatology · 2025
    6. Long‐Term Use of Tralokinumab in Patients With Atopic Dermatitis: A Real‐World Multicentric Case Series International Journal of Dermatology · 2025
    7. Tapinarof cream for atopic dermatitis: Pharmacokinetics, systemic exposure, and preliminary efficacy/safety results Journal of The American Academy of Dermatology · 2017
    8. Targeting the Janus Kinase Family in Autoimmune Skin Diseases Frontiers in Immunology · 2019 · 124 citations
    9. Validation of the Cutaneous Lupus Disease Area and Severity Index (CLASI) using physician- and patient-assessed health outcome measures Journal of the American Academy of Dermatology · 2012 · 40 citations
    10. Dupilumab Alters Both the Bacterial and Fungal Skin Microbiomes of Patients with Atopic Dermatitis Microorganisms · 2024 · 8 citations
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