This review found that surgical treatments such as laparoscopic ovarian drilling and transvaginal hydrolaparoscopy may help induce ovulation in over 50% of PCOS patients who are resistant to drug therapy, with more than 40% achieving pregnancy, though miscarriage and ectopic pregnancy rates were noted.
5 citations
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January 2021 in “Daru” This case report highlights a rare instance of severe multi-organ involvement following a single dose of methotrexate for ectopic pregnancy, requiring intensive care but ultimately successfully treated with leucovorin and supportive care.
1 citations
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January 2015 in “Case reports in endocrinology” This case report highlights that women with nonclassical congenital adrenal hyperplasia should be aware of the risk of having a child with classical CAH if their partner also carries a severe mutation.
29 citations
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December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses factors affecting fertility in both men and women with congenital adrenal hyperplasia and emphasizes individualized preconception management but reports no new clinical results.
August 2014 in “Warwick Research Archive Portal (University of Warwick)” This study found that obesity in women may impair endometrial stromal function and contribute to reproductive complications, possibly due to metabolic influences rather than immune cell differences.