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research Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evolutionary Development

1 citations, October 2013

Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine

60 citations, April 2012 in “Physiology”

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model

77 citations, April 2016 in “Science Advances”

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

research Organ Regeneration Based on Developmental Biology: Past and Future

21 citations, June 2018 in “Current Opinion in Genetics & Development”

Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.

research Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches

179 citations, April 2012 in “Nature Communications”

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

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community Verteporfin and Microneedling

in Treatments 5 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.