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research Tooth, Hair, and Claw: Comparing Epithelial Stem Cell Niches of Ectodermal Appendages

14 citations, February 2014 in “Experimental Cell Research”

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

research Early Inductive Events in Ectodermal Appendage Morphogenesis

160 citations, January 2014 in “Seminars in cell & developmental biology”

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

research Expression of Foxi3 Is Regulated by Ectodysplasin in Skin Appendage Placodes

43 citations, February 2013 in “Developmental dynamics”

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses

23 citations, November 2001 in “Archives of Dermatology”

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

research Keratinocyte-Specific Ablation of the NF-κB Regulatory Protein A20 (TNFAIP3) Reveals a Role in the Control of Epidermal Homeostasis

76 citations, May 2011 in “Cell death and differentiation”

A20 protein is crucial for normal skin and hair development.

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community Verteporfin and Microneedling

in Treatments 6 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.