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research Tooth, Hair, and Claw: Comparing Epithelial Stem Cell Niches of Ectodermal Appendages

14 citations , February 2014 in “Experimental Cell Research”

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

research Early Inductive Events in Ectodermal Appendage Morphogenesis

160 citations , January 2014 in “Seminars in cell & developmental biology”

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

research Organizational Principles of Integumentary Organs: Maximizing Variations for Effective Adaptation

8 citations , March 2025 in “Developmental Biology”

Integumentary organs adapt and evolve for survival, with potential uses in regenerative medicine.

research Expression of Foxi3 Is Regulated by Ectodysplasin in Skin Appendage Placodes

43 citations , February 2013 in “Developmental dynamics”

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses

23 citations , November 2001 in “Archives of Dermatology”

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

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community Hair loss research is a money grab

in Chat 217 upvotes 3 weeks ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community OFFICIAL Multi-Center Verteporfin Trial Recruitment

in Research/Science 250 upvotes 6 months ago

Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

community Verteporfin and Microneedling

in Treatments 1 year ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.