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GlossaryCD73 (ecto-5'-nucleotidase)

enzyme converting extracellular AMP to adenosine, impacting inflammation

CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of many cell types. It plays a crucial role in the immune system by converting extracellular AMP (adenosine monophosphate) into adenosine, which has anti-inflammatory effects. This enzyme is significant in various physiological processes, including tissue protection and repair, and is being studied for its potential role in cancer and autoimmune diseases.

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research The Adenosine-Generating Ecto-Enzyme CD73 Regulates Human Hair Growth

August 2016 in “Journal of Investigative Dermatology”

The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.

research A Network Pharmacology-Based Approach to Explore Mechanism of Action of Medicinal Herbs for Alopecia Treatment

8 citations , February 2022 in “Scientific Reports”

Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.

research The Adenosine-Generating Ecto-Enzyme, CD73, Functions as an Intrafollicular Regulator of Human Hair Growth

April 2016 in “Journal of Investigative Dermatology”

CD73 may regulate hair growth and could be targeted for hair growth treatments.

research Dormant Tumor Cells in Ret Transgenic Mouse Melanoma Model and Their Interaction with Memory T Cells

January 2012 in “heiDOK (Heidelberg University)”

Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.

STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

1 citations , August 2016 in “Journal of Investigative Dermatology”

Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.

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community Young guys read this

68 upvotes 7 years ago

A user's experience with dealing with hair loss, and the advice that was shared by other users to cope with it. Suggested treatments included shaving their head, using medications such as finasteride, minoxidil, and dutasteride, as well as dermarolling.

community Sensitive to Oral fin + RU. Am I screwed?

in Product 6 upvotes 4 years ago

Akinfenrawr experienced negative side effects from oral finasteride and RU58841, and is seeking alternative hair loss treatments. They discuss various options, including raloxifene, oral dutasteride, liposomal finasteride, Breezula, Pyrilutamide, SM04554, and sulforaphane, but have concerns about efficacy, availability, and cost.

community The ANSM is trying to ban Finasteride

in Research/Science 110 upvotes 5 months ago

France is considering reviewing finasteride and dutasteride due to concerns about their safety, but a ban in the EU is unlikely due to regulatory hurdles. Many users express frustration over the potential ban, emphasizing the effectiveness of finasteride for hair loss and criticizing the influence of anecdotal evidence on public health policy.