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      Exosomes and Hair Regeneration: A Systematic Review of Clinical Evidence Across Alopecia Types and Exosome Sources

      research Exosomes and Hair Regeneration: A Systematic Review of Clinical Evidence Across Alopecia Types and Exosome Sources

      September 2025 in “Clinical Cosmetic and Investigational Dermatology”
      This systematic review assesses the safety and effectiveness of mesenchymal stem cell (MSC)-derived exosome therapy for hair growth, focusing on androgenetic alopecia (AGA) and other hair loss types. It includes 11 studies with 298 patients, featuring various study designs. Exosomes from sources like adipose tissue, placenta, and foreskin showed improvements in hair density and thickness, with high patient satisfaction and minimal adverse effects. Notably, adipose-derived exosomes, especially when combined with microneedling, demonstrated significant efficacy. Despite promising results, the evidence is limited by study heterogeneity and small sample sizes, indicating a need for more standardized, high-quality randomized controlled trials to confirm these findings and establish treatment protocols.

      research Enzymes

      1 citations , November 2011 in “British journal of pharmacology”
      Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

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      community 22M. 4 months on minoxidil 5%, 2x a day

      in Progress Pictures  574 upvotes 1 year ago
      A 22-year-old man shared his 4-month progress using minoxidil 5% twice daily for hair loss, showing thicker hair without using finasteride. Others commented on his good results and discussed their own experiences with hair loss and treatments.

      community Dutasteride accelerated my hairloss, no shed tho

      in Finasteride/Dutasteride 6 months ago
      A user experienced worsening hair recession after adding 0.5 mg daily dutasteride to their regimen of topical minoxidil and finasteride, despite no initial shedding. They plan to continue monitoring the situation, as others suggest it may be too early to see results and recommend blood tests to check DHT levels.

      community I'm gonna be bald by 20 and I'm not even exagerrating. Wtf do I even do?

      in Chat  77 upvotes 2 years ago
      A 16-year-old is experiencing early male pattern baldness and is considering using Minoxidil now and Finasteride after turning 18. Another user shared a positive experience with topical Minoxidil and Finasteride, noting improvement in hair thickness and no side effects.