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GlossaryExtracellular Matrix Proteins (ECM Proteins)

provide structural and biochemical support to surrounding cells

Extracellular Matrix Proteins (ECM Proteins) are a group of molecules secreted by cells that provide structural and biochemical support to the surrounding cells. These proteins, such as collagen, elastin, and fibronectin, form a complex network that helps maintain tissue integrity, facilitates cell communication, and plays a crucial role in wound healing and tissue regeneration.

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The Enhancement of Dermal Papilla Cell Aggregation by Extracellular Matrix Proteins Through Effects on Cell–Substratum Adhesivity and Cell Motility

research The Enhancement of Dermal Papilla Cell Aggregation by Extracellular Matrix Proteins Through Effects on Cell–Substratum Adhesivity and Cell Motility

44 citations, June 2009 in “Biomaterials”

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.

research Dipeptidyl-Peptidase 4 (DPP4)-Positive Fibroblasts Are Responsible for Secretion of Pro-Fibrotic Matrix Proteins in Human Skin

April 2019 in “Journal of Investigative Dermatology”

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

research In Vitro Strategies for Mimicking Dynamic Cell–ECM Reciprocity in 3D Culture Models

June 2023 in “Frontiers in Bioengineering and Biotechnology”

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

research Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

25 citations, April 2012 in “Acta Biomaterialia”

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle

44 citations, June 2018 in “Journal of Cellular Physiology”

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

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community Minoxidil actually reduces wrinkles

in Research/Science 208 upvotes 4 days ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.