72 citations
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January 2007 in “Dermatology” This study found a correlation between moderate to extensive alopecia and low-grade inflammation, a cardiovascular risk marker, particularly in young men under 35 with central obesity.
1 citations
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December 2023 in “Experimental Dermatology” This study reported that 57.4% of children under 10 with early-onset alopecia areata experienced over 50% hair regrowth after treatment with topical corticosteroids, noting that those under 4 showed significantly better responses, although personal atopic history was the only differing prognostic factor.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report concludes that early-onset alopecia areata does not independently predict poorer long-term outcomes, with prognosis more strongly influenced by baseline severity and treatment response.
4 citations
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December 2021 in “Pharmacological Reports” This study found that metformin's metabolic benefits, such as reducing fat content and improving insulin sensitivity, were less pronounced in men with early-onset androgenic alopecia compared to those with normal hair growth, possibly due to differences in systemic inflammation and vitamin D status.
3 citations
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May 2021 in “Molecules” This study found that men with early-onset androgenetic alopecia may experience less benefit from rosuvastatin treatment in terms of improving cardiometabolic risk factors compared to men with normal hair growth.