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research LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway

53 citations , April 2016 in “Stem cell research & therapy”

This study reports that LL-37 treatment enhances cell proliferation, migration, and secretion of regenerative factors in adipose-derived stem cells, potentially promoting hair growth in vivo.

research Author response: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)

October 2021

This study identified the Arabidopsis cation chloride cotransporter CCC1 as essential for regulating pH and function in the trans-Golgi network/early endosome, with its absence causing significant growth and stress response defects.

research An Experimental Study of Morphofunctional Features of Hair Follicles Early Response in Cyclophosphamide-Induced Alopecia

September 2024 in “Journal of Anatomy and Histopathology”

In this study, researchers found that topical application of 3-β-methoxy-Δ18-oleanene (miliacin) in mice sped up the recovery of hair follicles damaged by cyclophosphamide, moving them into a new hair growth cycle more quickly compared to controls.

research Methodologic considerations in evaluating early clinical outcomes of GT20029 for androgenetic alopecia

January 2026 in “Journal of Dermatological Treatment”

This source discusses a Phase 2 trial by Hu et al. that evaluated the efficacy of topical GT20029 compared to a placebo, though the abstract does not provide specific results.

research γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection

1 citations , September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that skin-resident and recruited γδ T cells play a crucial role in an early wound healing response following cutaneous vaccinia virus infection, rather than in controlling virus replication.

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community Weird response to microneedling

in Microneedling 40 upvotes 1 year ago

Microneedling can cause sneezing and eye tearing due to nerve stimulation, particularly near the temples and forehead. Some users find it lessens over time, while others prefer using finasteride and minoxidil for hair growth.

community 2.5 months on Oral Minoxidil (2.5mg) + Finasteride (1mg) - Early signs of progress? And also estrogen level change

10 upvotes 2 months ago

The user has been using 2.5mg oral minoxidil and 1mg finasteride daily for 2.5 months, noticing increased hair density and new hair growth. There is concern about elevated estradiol levels, possibly due to finasteride, but no significant side effects have been reported yet.

community 3 months, 1mg Fin & 5mg oral Min. early days but can i expect the baby hairs to grow out and crown to improve?

in Progress Pictures 97 upvotes 2 years ago

A user shared progress pictures after 3 months of using 1mg finasteride and 5mg oral minoxidil, asking if baby hairs will grow and the crown will improve. Replies praised the noticeable growth and expressed hope for continued improvement.

community People are misunderstanding PP405. 31% response at 8 weeks is better than you think

181 upvotes 1 year ago

PP405 shows promise as a hair loss treatment, with 31% experiencing increased hair density in a short trial. It may complement treatments like finasteride and minoxidil, but long-term effectiveness and safety need confirmation.

community 23M – 107 days on dutasteride (0.5mg/day) + minoxidil. Any real progress or too early?

in Is this regrowth? 116 upvotes 9 months ago

A 23-year-old male has been using dutasteride (0.5mg daily) and minoxidil with tretinoin for 107 days to address crown hair loss, noticing slight thickening but uncertain progress. He reports no shedding or side effects, experiencing positive effects like improved skin texture and increased energy.

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