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Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis

research Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis

53 citations , August 2019 in “American journal of human genetics”

This study found that FOXN1 haploinsufficiency is a significant genetic factor causing T cell lymphopenia at birth, linked to reduced thymic function in both humans and mice.

research Secondary Neoplasm Arising in Nevus Sebaceus of Jadassohn: A Case Report Emphasizing Early Recognition and Evaluation

March 2026 in “Scientific Journal”

This case study reported a 15-year-old girl with a nevus sebaceus of Jadassohn, where a secondary neoplasm potentially developed into either pigmented trichoblastoma or pigmented basal cell carcinoma, highlighting the importance of early recognition and evaluation of such lesions for effective management.

research Pathophysiology of the Burn Scar

10 citations , January 2018 in “Elsevier eBooks”

This review discusses the wound healing process and the factors contributing to abnormal scarring after thermal injuries, but it reports no new clinical results.

research Hidradenitis suppurativa: pathogenesis and management

238 citations , July 2003 in “British Journal of Plastic Surgery”

This review discusses the importance of early diagnosis and the management of hidradenitis suppurativa, reporting no new clinical results but highlighting current therapeutic approaches and need for collaboration in treatment.

research Hidradenitis suppurativa: A comparison of guidelines

4 citations , January 2018 in “Journal of dermatology & dermatologic surgery”

This review compares European and U.S. treatment guidelines for hidradenitis suppurativa and reports no definitive standard, highlighting the need for more randomized controlled trials.

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Community Join

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community Daily Mail article - How I REVERSED my balding. My barber called my thick head of hair a 'miracle'... this is exactly how I did it:

in Finasteride/Dutasteride 1 upvotes 1 year ago

Finasteride and a hair transplant were used to reverse hair loss, leading to thicker hair and increased confidence. The user received compliments on their improved appearance.

community Early onset diffuse thinners + nonresponders to oral meds?

7 upvotes 1 week ago

A 19-year-old has been experiencing diffuse thinning since age 16 and has not seen improvement despite using minoxidil, finasteride, dutasteride, and other treatments. Suggestions include increasing dutasteride dosage, using RU58841, and considering topical treatments or a hair transplant.

community Early Duntasteride adoption -- trying again now

in Progress Pictures 30 upvotes 1 month ago

A user shared their experience with hair loss treatments, initially using oral dutasteride (Avodart) and minoxidil, and recently switching to a topical dutasteride solution. They reported significant hair improvement over time and are hopeful about the new topical treatment.

community Early 2 months results Fin/min/1.5mmm

in Progress Pictures 28 upvotes 1 month ago

The user shared early progress pictures after two months of using 1mg oral finasteride, 5% topical minoxidil, and a 1.5mm dermapen weekly. They reported no significant progress on the temples and forehead hairline but will update later.

community early 20s, hair thinning, looking for natural remedies not expensive soaps

in Female 3 months ago

The user is experiencing hair thinning and prefers natural remedies over expensive shampoos. Other users suggest that natural remedies are ineffective and recommend medications like minoxidil and finasteride, while also considering diet and lifestyle changes.

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Learn

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learn Stemoxydine

Is stemoxydine effective for early-stage thinning and alopecia? Stemoxydine may help improve hair density in early-stage thinning and alopecia.

learn Omega 3

Can a shampoo with omega-3s help thicken those early thinning spots? Shampoos with omega-3s may improve scalp health but won't thicken hair directly.

learn Ecklonia Cava

Can Ecklonia Cava be used as a preventive treatment for early signs of hair thinning? No human trial has tested Ecklonia cava for hair loss, so it cannot be called preventive; the evidence is mouse studies and cell cultures suggesting antioxidant activity and 5-alpha-reductase inhibition in the lab.

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