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This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.

In this study, researchers found that glycan profiles in epidermal stem cells differed between young and old mice, suggesting these changes may serve as molecular markers for aging.

This study discusses how redox imbalance, specifically through reduced Insulin-like Growth Factor-1 mediated by the transcription factor JunB and sphingolipid metabolism changes, contributes to skin aging by depleting stem cell pools and altering the extracellular matrix, ultimately impacting skin integrity and function.

This review highlights essential preoperative assessments for ophthalmologists and non-oculo-facial surgeons performing upper facial rejuvenation, emphasizing the importance of understanding ocular and periocular anatomy to achieve both cosmetic and functional improvements.

This review discusses the interplay between polycystic ovary syndrome, aging, and fertility in women, and reports no new clinical results; the authors highlight pathways and interventions needing further research.