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This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.

In this study, fraction No. 3 of Oryza sativa bran extract demonstrated high unsaturated fatty acid content and significant 5α-reductase inhibition, suggesting potential for developing anti-androgenic alopecia products.

This study found that standardized para rubber seed oil may be a safe and effective bio-oil for stimulating hair growth and reducing hair loss, exhibiting comparable effects to minoxidil, dutasteride, and vitamin C in certain laboratory settings.

This study suggests that extracellular vesicles from prostate cancer cells could aid in identifying tumor heterogeneity and serve as biomarkers, while also playing a role in SARS-CoV-2 infection in nasopharyngeal mucus.

This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.