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GlossaryDihydrotestosterone (DTT)

potent androgen hormone derived from testosterone

Dihydrotestosterone (DHT) is a potent androgen hormone derived from testosterone through the action of the enzyme 5-alpha-reductase. It plays a crucial role in the development of male characteristics and is also implicated in conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia.

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research Characterization of Low Abundance Wool Proteins Through Novel Differential Extraction Techniques

26 citations , June 2010 in “Electrophoresis”

New techniques helped identify rare wool proteins by reducing dominant ones.

research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts

9 citations , March 2019 in “Molecular & cellular proteomics”

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

research Estimating the Burden of Skin Diseases Using Patient-Reported Daily Time Trade-Off as a Measure of Disease Impact and Unmet Needs

January 2024 in “JEADV Clinical Practice”

Patients with certain skin diseases are willing to spend significant time on treatment, indicating a high impact on their lives and a need for better treatments.

research Inheritance of Some Electrophoretic Phenotypes of Human Hair

January 1990 in “Advances in forensic haemogenetics”

Human hair protein patterns are inherited genetically.

research Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction

15 citations , February 1999 in “The anatomical record”

Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.

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