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This study found that more than 70% of patients with autoimmune blistering diseases experienced alopecia, with about 10% having scarring alopecia, and elevated Dsg1 ratios were linked to hair loss in pemphigus vulgaris.

This study found that deleting all three Desmoglein 1 genes in mice led to impaired skin barrier function, disorganized epidermis, and postnatal lethality, highlighting Dsg1's essential role in epidermal development and maintenance.

This study developed and characterized new mouse models of Pemphigus that mimic different forms of the disease, but treatment with Methyl-Prednisolone showed only partial effectiveness.

In this study, researchers found that the variability in growth factor expression, particularly TGFβ1, in PRP samples could influence patient responses to hair loss treatment with PRP therapy.

This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.