82 citations
,
January 1997 in “Forensic science international” This article presents a biochemical model to explain how drug molecules are incorporated into hair, highlighting factors such as drug melanin affinity and the role of physico-chemical properties.
17 citations
,
May 2007 in “Forensic Science Medicine and Pathology” This study reported that clozapine and its metabolite showed a preference for binding to pigmented hair, but were also detectable in non-pigmented hair of patients with Parkinson's, with high correlations between dose and hair concentration.
47 citations
,
June 1996 in “International Journal of Legal Medicine” This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.
20 citations
,
October 2018 in “American Journal of Clinical Dermatology” This article reviews drug-induced pigmentation and reports no new clinical findings, highlighting difficulty in confirming drug associations due to factors like delayed onset and polypharmacy.
53 citations
,
November 1997 in “Journal of Forensic Sciences” This study found that codeine incorporation in guinea pig hair varied with pigmentation and was highest in black hair, suggesting the role of eumelanins in drug binding.
