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Research

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research 686 Evaluation of contamination and quantification of drug penetrations studies using Quantitative Mass Spectrometry Imaging

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.

research Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation

28 citations , February 2016 in “International Journal of Nanomedicine”

This study found that freeze-dried finasteride nanoparticles improved the stability, solubility, and in vitro dissolution of the drug, indicating potential benefits for poorly water-soluble drugs.

research 144 Evaluation of contamination and quantification of drug penetrations studies using Quantitative Mass Spectrometry Imaging

September 2017 in “Journal of Investigative Dermatology”

QMSI effectively maps and quantifies drug distribution in skin tissues.

research Drug safety evaluation of exemestane

7 citations , March 2011 in “Expert Opinion on Drug Safety”

This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.

research Design and evaluation of adapalene microemulsion for transfollicular drug delivery through guinea pig skin

4 citations , July 2023 in “Journal of Cosmetic Dermatology”

This study found that adapalene-loaded microemulsions significantly enhanced the drug's penetration through guinea pig skin compared to an aqueous suspension, with factors like surfactant ratios and the water-oil phase balance affecting the transfollicular drug delivery efficiency.

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community Evaluating Hair Regrowth Possibilities After Long-Term Hair Loss

in Basic Questions 229 upvotes 5 months ago

The user is concerned about hair loss and is considering treatments like finasteride and minoxidil but is unsure about their effectiveness and side effects. They have experienced mixed reactions to shaving their head and are struggling with confidence due to balding.

community PP405 Drug in Action: Picture From Official Company Website

780 upvotes 1 year ago

PP405 shows promise for hair follicle reactivation with minimal side effects. Users recommend continuing Minoxidil and Finasteride until more results are confirmed.

community A New Hair Loss Drug Could Cure Balding and Reverse Graying

367 upvotes 11 months ago

ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.

community Haircafe - TOPICAL minoxidil is an anti aging drug

in Minoxidil 245 upvotes 1 year ago

Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

community Wouldn’t it be funny if there already was a drug that existed which reactivated sleeping follicles? It would be our own version of Ozempic

202 upvotes 1 year ago

PP405 shows promise for reactivating hair follicles, with potential maintenance using 5AR inhibitors. Current treatments like Minoxidil and finasteride are effective but have limitations, and there is hope for more effective solutions in the future.

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learn Thymosin Beta 4

learn Baricitinib

Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib, an arthritis drug, was FDA-approved in 2022 for adults with severe alopecia areata after trials in which about a third of patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and regrowth is usually lost when it is stopped.

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Clinics

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Hair Loss Treatments
Dr Joydeep Roy's Skin Clinic, New S.S.Medicos, (near Cachar high school), Malugram/ Drugs Corner, itkhola near Cachar CollegeSilchar, Assam · IN

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