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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

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      community 18 months Dut - Shed after shed without any gains

      in Update  115 upvotes 1 month ago
      Dutasteride caused persistent hair shedding and no improvement for 18 months, leading to a switch back to finasteride. The user also uses oral minoxidil and plans to focus on better scalp health.

      community The homeless crackhead protocol

      in Satire  4324 upvotes 1 week ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.