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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 5 resultslearn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
learn GT20029
research compound made to degrade androgen receptors in scalp
learn Alopecia Areata
autoimmune disorder causing patchy hair loss
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natural substance from Neem tree with medicinal and pesticidal properties
Research
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research Regeneration, Wound Healing, and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
research Genetic Transformation of Keratoacanthoma-Type Cutaneous Squamous Cell Carcinoma Following Intralesional Chemotherapy
Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Clonal Analysis of Stem Cells in Differentiation and Disease
New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.
research Mutational Landscape of Extramammary Paget Disease
The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
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5 / 821 resultscommunity Can a folate deficiency make androgenetic alopecia worse?
The user is treating androgenetic alopecia with finasteride and discovered a folic acid deficiency. They are asking if curing the deficiency can worsen or improve their hair condition.
community People need to start accepting that only medical therapy (Fin/Dut) can save your hair in the long run.
Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.
community Why do we get bald from evolutionary perspective
Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.
community If PP405 goes systemic this would be quite catastrophic
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.
community The meds work: my dad at 23 yo vs me at 35 yo
Finasteride and oral minoxidil effectively maintain a youthful appearance and full head of hair, despite genetic predispositions to balding. The discussion also considers the impact of DHT blockers on masculinity and aging, with lifestyle choices like sunscreen use and a vegetarian diet mentioned.