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research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
research Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model
Human hair keratin helps repair nerve damage in rats.
research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons
GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
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5 / 1000+ resultscommunity Blaming Finasteride doesn't help you solve anything: dry eyes
Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.
community microinflammation caused by mometasone furoate?
The user experienced microinflammation on the crown after using mometasone furoate (Nasonex) nasal spray. They are seeking information on the relationship between this corticosteroid and hair loss.
community Finasteride (0.5mg) & Topical Minoxidil Progress over 2.5 years
The conclusion of the conversation is that the user, AdamC11, has been using finasteride (0.5mg daily) and topical minoxidil for 2.5 years and has seen good progression and maintenance with no negative effects. They plan to continue with their current treatments as long as their hair holds, and will consider more potent treatments if they start losing ground.
community New hack? Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes
The conversation discusses how Tretinoin may improve the effectiveness of Minoxidil for treating hair loss by increasing the activity of certain enzymes in hair follicles. One user comments that this information is not new.
community ~6 years on Fin + 3 years of Min. Seeing zero progress.
The user has been using finasteride for six years and minoxidil for three years with no noticeable hair regrowth. Suggestions include switching to dutasteride, considering a hair transplant, and trying microneedling.