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Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration

research Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration

62 citations, February 2016 in “ACS Applied Materials & Interfaces”

Technique creates 3D cell spheroids for hair-follicle regeneration.

research Can an In Vitro Hair Drug Model Be Developed Using Dermal Papilla Cells Alone?

3 citations, February 2021 in “Experimental dermatology”

Dermal papilla microtissues could be useful for initial hair growth drug testing.

The Enhancement of Dermal Papilla Cell Aggregation by Extracellular Matrix Proteins Through Effects on Cell–Substratum Adhesivity and Cell Motility

research The Enhancement of Dermal Papilla Cell Aggregation by Extracellular Matrix Proteins Through Effects on Cell–Substratum Adhesivity and Cell Motility

44 citations, June 2009 in “Biomaterials”

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.

research Large-Scale Cultivation of Transplantable Dermal Papilla Cellular Aggregates Using Microfabricated PDMS Arrays

25 citations, August 2010 in “Acta Biomaterialia”

Researchers developed a method to grow hair follicle cells for transplantation using a special chip.

research Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture

46 citations, September 2014 in “Tissue engineering. Part A”

Researchers created hair-inducing human cell clusters using a 3D culture method.

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Community Join

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community Information regarding Follicusan DP?

in Product 3 upvotes 1 year ago

Follicusan DP is discussed as a potential alternative to Minoxidil without side effects, but information is scarce. It is noted to be of German origin and details on its mechanism are limited.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 2 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

6 upvotes 5 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community Show of hands (US people), who's ordering pyrilutamide?

in Treatment 6 upvotes 6 months ago

People are discussing ordering pyrilutamide for hair loss treatment in the US. The treatment is from Kintor's subsidiary company and is available on Amazon.

community Hair Growth Journey: 10 months

in Progress Pictures 252 upvotes 8 months ago

A 31-year-old who experienced severe hair loss during medical school tried various treatments, including topical and oral finasteride and minoxidil, but stopped due to side effects. They restarted treatment 10 months ago with a regimen including topical finasteride, minoxidil, retinoic acid, hydrocortisone, oral minoxidil, and light therapy, emphasizing the importance of consistency and skincare.

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