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      research High-Dose Mizoribine Treatment for Adolescents with Systemic Lupus Erythematosus

      16 citations , April 2006 in “Pediatrics International”
      The study investigated the use of high-dose mizoribine (MZR) at 300 mg/day in five adolescents with systemic lupus erythematosus (SLE), which was double the conventional adult dose. The treatment aimed to achieve remission while minimizing the adverse effects associated with prolonged immunosuppressant use. The results indicated that high-dose MZR was effective in controlling symptoms and reducing steroid dependency, with satisfactory efficacy observed in all patients. Side effects included hyperuricemia in two patients, which was managed by dose adjustment or resolved spontaneously, and temporary hair loss in two patients, which subsided after a few months. The study concluded that high-dose MZR could be administered effectively and safely, with necessary monitoring of serum uric acid levels, suggesting its potential application for steroid-dependent pediatric SLE patients.
      Morning Periorbital Edema Due to Low Dose Oral Minoxidil

      research Morning Periorbital Edema Due to Low Dose Oral Minoxidil

      April 2023 in “Actas Dermo-Sifiliográficas”
      Low doses of oral minoxidil, a hair loss treatment, can cause temporary morning swelling around the eyes, but it's not serious and can disappear with continued use or dose adjustment.

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