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This study found that prolonged topical application of minoxidil significantly increased skin flap survival in rats by promoting angiogenesis compared to shorter application or a saline control.

This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.

This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.

This study used multiphoton microscopy to successfully visualize rabbit skin microstructure, highlighting its noninvasive potential for future skin research related to diseases and wound healing.

Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.