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Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite

research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite

39 citations, April 2007 in “Therapeutic Drug Monitoring”

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease

27 citations, May 2015 in “Neuropharmacology”

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

research 5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

26 citations, September 2018 in “Neurobiology of Disease”

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

research Dopamine Is a Novel, Direct Inducer of Catagen in Human Scalp Hair Follicles In Vitro

19 citations, November 2012 in “British Journal of Dermatology”

Dopamine stops hair growth and pigment production in human scalp hair follicles.

research Telogen Effluvium Associated with the Dopamine Agonist Pramipexole in a 55-Year-Old Woman with Parkinson's Disease

14 citations, October 2006 in “Journal of The American Academy of Dermatology”

A woman with Parkinson's disease experienced hair loss from the Parkinson's medication pramipexole, which improved after stopping the drug.

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Community Join

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community Mucuna pruriens, dopamine and prolactin. Natural route with oils.

in Treatment 2 upvotes 1 year ago

The post discusses using Mucuna pruriens, essential oils, and dermarolling for hair loss treatment. The user also mentions pausing testosterone-boosting herbs due to side effects like acne and hair loss.

community Dutasteride is possibly BETTER for the brain than Finasteride

in Finasteride/Dutasteride 23 upvotes 8 months ago

Dutasteride may be better for the brain than Finasteride, potentially increasing dopamine levels and causing fewer side effects. For those switching from Finasteride to Dutasteride to prevent hair loss, it's recommended to continue Finasteride for 3-4 months while starting Dutasteride to avoid shedding due to Dutasteride's long half-life.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 42 upvotes 5 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

community 3 months hair transformation: From finasteride to dutasteride, minoxidil, ketoconazole shampoo, and dermarolling.

in Progress Pictures 71 upvotes 1 year ago

The conclusion of this conversation is that the user experienced hair shedding while taking finasteride for 2 years, but after switching to dutasteride, using minoxidil, ketoconazole shampoo, and dermarolling, their hair has become thicker and hair loss has completely stopped. They also mentioned having no side effects from dutasteride.

community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

in Progress Pictures 118 upvotes 3 months ago

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

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