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Efficacy of Dupilumab in Treating Atopic Dermatitis With Recurrent Eczema Herpeticum in a Patient With DOCK8-Deficiency Hyper-IgE Syndrome: A Case Report

research Efficacy of Dupilumab in Treating Atopic Dermatitis With Recurrent Eczema Herpeticum in a Patient With DOCK8-Deficiency Hyper-IgE Syndrome: A Case Report

August 2023 in “Cureus”

Dupilumab helped improve skin and prevent new lesions in a child with a rare immune disorder and severe eczema.

research British Society for Pediatric Dermatology Annual Meeting, Sheffield, 18-19 November 2016

December 2016 in “British Journal of Dermatology”

The meeting highlighted the importance of genetic testing and multidisciplinary approaches in pediatric dermatology.

research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates

21 citations, January 2020 in “General and Comparative Endocrinology”

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations, October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss

30 citations, October 2015 in “Journal of Ethnopharmacology”

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

View more "dock8-deficiency" in research →

Community Join

4 / 4 results

community C’est terrible - at my wits end

Desperate-War-3925 in Female 447 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

Thelondonvoyager in Finasteride/Dutasteride 113 upvotes 2 years ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community What makes breezula different than formula 82f?

illmatic_xxi in Question 8 upvotes 5 years ago

Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

community What do we actually know about HMI-115?

Shenanigan_n_again in Chat 16 upvotes 1 year ago

The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.