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research Laser microdissection and DNA typing of cells from single hair follicles

45 citations , December 2004 in “Forensic Science International”

This study reports that using laser microdissection to isolate telogen hair follicles significantly improves DNA extraction efficiency for STR typing, reducing contamination from keratin.

Impact of Sonication Washing on Nuclei Counts in Hair Roots

research Hair root sonication washing impact on nuclei counts

February 2025 in “Journal of Forensic Sciences”

The study found that sonication washing of hair roots with fewer than 50 visible nuclei could reduce the number of nuclei available for DNA extraction and STR typing, suggesting that for laboratories focused on nuDNA analysis, a gentler washing method might be adequate.

research Validation and casework testing of the BioPlex-11 for STR typing of telogen hair roots

36 citations , November 2005 in “Forensic Science International”

This study developed a new STR typing strategy for forensic casework, enabling the simultaneous analysis of 11 polymorphic systems, particularly useful for limited or degraded DNA samples such as telogen hair roots.

research The Ultrastructure of Tissue Attached to Telogen Hair Roots

6 citations , August 2008 in “Journal of Forensic Sciences”

This study used electron microscopy to characterize tissues on telogen hair roots, finding that tissue quality, including nucleated and nonnucleated epithelial cells, may play a crucial role in DNA typing for forensic analysis.

research Uncharted waters

4 citations , February 2018 in “EMBO reports”

This discussion highlights the potential of next-generation sequencing in forensic science for predicting phenotypic traits from DNA samples, but reports no new clinical results and underscores ongoing ethical and legal challenges.

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community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Haunting study is making me considering cycling fin/dut

in Research/Science 158 upvotes 1 year ago

Concerns about the long-term effects of dutasteride and finasteride on fertility, with discussions on cycling these medications to mitigate risks. The conversation highlights skepticism about study methodologies and the importance of weighing treatment risks against potential fertility issues.

community 3 and a half month progress pic

260 upvotes 1 year ago

The user shared a 3.5-month hair regrowth update using finasteride, 5% topical minoxidil, micro-needling, and keto shampoo, along with lifestyle changes like reducing stress and improving diet. They encourage others to stay committed to their regimen despite initial slow progress.

community Why do so many dudes wait until they are literally BALD to start treatment

in Chat 552 upvotes 1 year ago

Many delay hair loss treatment due to lack of awareness, denial, or fear of side effects. Treatments like finasteride, minoxidil (oral and topical), and hair transplants are discussed, with mixed results and concerns about side effects.

community DNA test result is incredible !

in Technology 31 upvotes 7 months ago

The conversation discusses a personalized hair loss treatment plan based on DNA test results, recommending Minoxidil, Dutasteride, 17-alpha Estradiol, Cetirizine, and PRP sessions. The test identifies a high risk of hair loss due to DHT but a good response to Minoxidil, suggesting a tailored approach to treatment.

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