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GlossaryDNA synthesis

process of creating an exact copy of DNA

DNA synthesis, also known as DNA replication, is the process by which a cell makes an exact copy of its DNA. This is crucial for cell division, allowing each new cell to have the same genetic information as the parent cell. The process involves unwinding the double helix, using each strand as a template to build a new complementary strand, and is facilitated by enzymes like DNA polymerase.

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research Bisindolylmaleimide Protein Kinase C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures

11 citations, January 1997 in “Skin Pharmacology and Physiology”

A certain inhibitor can slow down the decrease in DNA creation in mouse hair follicles, which might help with hair growth.

research Chemical Agents and Peptides Affect Hair Growth

23 citations, July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain chemicals and peptides can promote hair growth or prevent baldness.

research Experimental Study on the Effects of Spironolactone on Human Hair Follicles In Vitro

January 2006

Spironolactone does not change hair growth.

research Influence of Melatonin on HaCaT Cell Proliferation Measured by Means of ATP Bioluminescence and Fluorometric Assays

November 2002

Melatonin affects cell growth differently based on its concentration.

Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ

research Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ

11 citations, July 2015 in “Gene”

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

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community 137 years old and still far more hair than the average r/tressless user

in Satire 1063 upvotes 1 year ago

The post and conversation are about a user claiming to be 137 years old with a full head of hair. Specific treatments mentioned include dutasteride, RU58841, and minoxidil.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 668 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

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