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Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence

research Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence

January 2024 in “GeroScience”

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging

25 citations, November 2014 in “Ageing Research Reviews”

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

research Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia Through Overgrowth of Lactobacillus Murinus in Mice

82 citations, August 2017 in “Cell Reports”

An imbalanced gut and lack of biotin can cause hair loss in mice.

research A Cross-Sectional Study of Plasma Trace Elements and Vitamins Content in Androgenetic Alopecia in Men

3 citations, November 2020 in “Biological Trace Element Research”

Men with hair loss may lack zinc, copper, and vitamin D; supplements could help.

research Anti-Graying Effects of External and Internal Treatments with Luteolin on Hair in Model Mice

December 2024 in “Antioxidants”

Luteolin can reduce hair graying in mice, with external treatment being more effective.

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Community Join

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community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community 5 month update on my all natural protocol

in Update 7 upvotes 6 years ago

The user updated on their all-natural hair loss protocol, which includes massages, LLLT, Ashwagandha, Supergreens mix, Vitamin D, Castor Oil + DMSO, a specific diet, and headstands. They reported some hair regrowth and improved hair quality, with plans to continue the regimen and monitor results.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 7 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 73 upvotes 4 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community Wtf have we been doing for the last 30 years

in Treatment 526 upvotes 4 days ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

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