research Skin-specific transgenic overexpression of ovine β-catenin in mice
This study found that overexpression of ovine β-catenin in transgenic mice increased hair follicle density by promoting the transition from catagen to anagen.
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5 / 1000+ resultsresearch Subchronic study of sperm morphology, genotoxic and mutagenic effect of Lepidium sativum seeds aqueous extract in vivo
In this study, high doses of Lepidium sativum seeds extract were reported to cause toxicity and tissue damage in animals, suggesting the need for careful use under medical supervision.
research Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes
This study suggests that geranyl acetate may offer protective, anti-inflammatory, and cytoprotective effects against PPD-induced toxicity in keratinocyte cells, indicating its potential as a plant-derived treatment.
research Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling
This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.
research Flavonoids in safflower extract reduce cisplatin-induced damage to human follicle dermal papilla cells by inhibiting DNA damage and Rad17/Chk1/Cdc25C signaling
The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.
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5 / 170 resultscommunity Do you guys believe oral minoxidil causes faster aging of the face? (By mechanism like bloating, dark circles, and inhibition of collagen)
Oral minoxidil may cause facial bloating and dark circles, making some users feel they look older. Some consider reducing the dosage or switching treatments due to these side effects.
community Do you Have Poor Posture? Maybe Contributing to Hair Loss , Esp Diffuse Thinning
Correcting posture may improve hair health by enhancing blood circulation and reducing side effects like bloating and sexual issues. The user has been using minoxidil and finasteride for two years with underwhelming results and is exploring posture correction as a potential aid.
community Day 1 vs 6 months vs 1 year vs 2 years. Finasteride, minoxidil and derma rolling.
A user documented their two-year hair regrowth journey using finasteride, minoxidil, and derma rolling, showing significant improvement. They switched from topical to oral minoxidil after the first year, experiencing some shedding and minor bloating.
community Dutasteride Infertility Debunked: Low T causes true infertility.
Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.
community Doctor says i shouldn't take fin because its "hormonal"
A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.
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