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research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

48 citations , September 2020 in “Frontiers in Immunology”

In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.

research Acquired immunogenicity of DNA after modification with malondialdehyde in patients with alopecia areata

10 citations , March 2014 in “Scandinavian journal of clinical and laboratory investigation”

This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.

research Immune-mediated Coombs negative intravascular haemolysis in systemic lupus erythematosus (SLE)

August 2021 in “BMJ Case Reports”

This case report details a 27-year-old woman's diagnosis of systemic lupus erythematosus with immune-mediated intravascular haemolysis, which improved with steroid treatment.

research Clinical analysis of rash in systemic lupus erythematosus

February 2018 in “Chin J Clinicians(Electronic Edition)”

This study found that rash in SLE patients is prevalent and associated with more severe disease indicators, including certain clinical manifestations and serological abnormalities.

research Systemic Lupus Erythematosus—Vasculopathy/Vasculitis, Susac Syndrome, and Myasthenia Gravis

December 2010 in “Elsevier eBooks”

This article discusses the clinical manifestations of systemic lupus erythematosus and their potential mechanisms, but reports no new experimental results.

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community Androgen degraders for hair loss

61 upvotes 2 years ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community Losing a ton consistently after 8 months dut please help me I don’t know what to do anymore, nothing works

in Chat 76 upvotes 1 year ago

A 20-year-old is experiencing hair loss despite using dutasteride and oral minoxidil. Suggestions include consulting a specialist, considering RU58841, and checking for other conditions and vitamin deficiencies.

community How is this even possible that there is no cure till now

in Technology 155 upvotes 4 months ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 5 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community DNA test result is incredible !

in Technology 31 upvotes 7 months ago

The conversation discusses a personalized hair loss treatment plan based on DNA test results, recommending Minoxidil, Dutasteride, 17-alpha Estradiol, Cetirizine, and PRP sessions. The test identifies a high risk of hair loss due to DHT but a good response to Minoxidil, suggesting a tailored approach to treatment.

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