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GlossaryMedroxyprogesterone Acetate (DMPA)

synthetic hormone used in contraceptives and hormone therapy

Medroxyprogesterone Acetate (MPA) is a synthetic form of the hormone progesterone, commonly used in hormonal contraceptives like Depo-Provera and in hormone replacement therapy. It works by preventing ovulation, thickening cervical mucus to block sperm, and altering the uterine lining to prevent pregnancy. Additionally, MPA is used to treat conditions like endometriosis and abnormal uterine bleeding.

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research Management of Clinical Side Effects of Depot Medroxyprogesterone Acetate

7 citations, August 2000 in “Journal of Pediatric and Adolescent Gynecology”

To improve use of the contraceptive DMPA among adolescents, effectively manage side effects like menstrual changes and weight gain through counseling and guidance.

Effects of Depot Medroxyprogesterone Acetate, the Copper IUD, and the Levonorgestrel Implant on Testosterone, Sex Hormone Binding Globulin, and Free Testosterone Levels: Ancillary Study of the ECHO Randomized Clinical Trial

research Effects of Depot Medroxyprogesterone Acetate, the Copper IUD, and the Levonorgestrel Implant on Testosterone, Sex Hormone Binding Globulin, and Free Testosterone Levels: Ancillary Study of the ECHO Randomized Clinical Trial

March 2024 in “BMC women's health”

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

research A 17-Year-Old Mother Seeking Contraception

8 citations, October 1996 in “JAMA”

The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.

research The Pediatrician and the Sexually Active Adolescent

3 citations, December 1997 in “Pediatric Clinics of North America”

Pediatricians should advise sexually active teens on safe sex and STD prevention, and discuss contraceptive options and their side effects.

research Basics of Hormonal Contraception

August 2010 in “Springer eBooks”

Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.

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