August 2025 in “Journal of Cosmetic Dermatology” In this study, a DMG-Na and caffeine-containing shampoo significantly reduced hair loss and increased hair density in men with male pattern hair loss over 6 months, compared to a placebo, without adverse effects.
18 citations
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April 1998 in “MIT Press eBooks” This study found that topical application of N,N-dimethylglycine sodium salt increased dermal blood flow and velocity in human subjects, likely through its effects on endothelial cells and NO-dependent vasodilation.
7 citations
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January 2021 in “Frontiers in genetics” This study suggests an association between DNA methylation changes in hair follicles and inherited color dilution in Rex rabbits, contributing to a deeper understanding of epigenetic influences on rabbit pigmentation.
1 citations
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January 2020 in “Research Square (Research Square)” This study found that inherited color dilution in Rex rabbit hair follicles is associated with DNA methylation changes, contributing to understanding the epigenetic regulation of rabbit pigmentation.
January 2026 in “British Journal of Dermatology” This study found that neither caffeine nor N,N-dimethylglycine treatments were toxic to balding or nonbalding dermal papilla cells and could stimulate calcium influx, indicating treatment responsiveness.