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research Clinical, Trichoscopic and Immunohistochemical Evaluation of Autologous Adipose-Derived Adult Stem Cell Injection in the Treatment of Female Pattern Hair Loss

October 2021 in “QJM: An International Journal of Medicine”

ADSC injections improve hair density, thickness, and reduce inflammation in female pattern hair loss.

Successful Treatment of Female Pattern Hair Loss with Injection of Autologous Adipose-Derived Adult Stem Cells: A Controlled Clinical, Trichoscopic, and Immunohistochemical Trial

research Successful Treatment of Female Pattern Hair Loss with Injection of Autologous Adipose-Derived Adult Stem Cells: A Controlled Clinical, Trichoscopic, and Immunohistochemical Trial

March 2025 in “International Journal of Trichology”

Injecting stem cells from a patient's own fat can improve hair growth in women with hair loss.

research Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells

1 citations , October 2021 in “Clinical, Cosmetic and Investigational Dermatology”

Vitamin B3 may help prevent hair loss and promote hair growth by protecting scalp cells from stress and reducing hair growth-blocking proteins.

research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes

171 citations , July 2007 in “Journal of Investigative Dermatology”

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

research Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

4 citations , July 2020 in “Biochemical and Biophysical Research Communications”

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

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5 / 34 results

community Has anyone used Magnesium L-Threonate ?

71 upvotes 7 years ago

Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 95 upvotes 3 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community A Theory on Why Microneedling Works

170 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community Did somebody of you start to go in the gym during your hairloss fight?

in Finasteride/Dutasteride 29 upvotes 2 years ago

A 19-year-old paused weightlifting due to hair loss concerns, using finasteride to improve hair condition. Others advised continuing gym workouts while using finasteride, as it doesn't harm hair, and emphasized focusing on fitness and confidence.

community Will Pp405 be the Ozempic of bald Guys

in Research/Science 101 upvotes 2 weeks ago

PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

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