research Establishment of a Culture Model for the Prolonged Maintenance of Chicken Feather Follicles Structure In Vitro
Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
Search
forLearn
0 / 0 results — no results
Research
5 / 88 results research Gene Expression Profiles of Melanocytes Over-Expressing miR-5110 in Alpaca
This study investigated the molecular mechanisms of pigmentation in alpaca melanocytes over-expressing miR-5110. Using high-throughput RNA sequencing, researchers identified 91,976 unigenes, with 13,262 exceeding 2000 nucleotides. Key pathways related to melanogenesis, including MAPK, Wnt, and cAMP signaling, were identified. Compared to controls, 162 genes were upregulated and 41 downregulated in miR-5110 over-expressed melanocytes. Differential expressions of genes such as DKK3, Pmel, IGF1R, CDK5, Ednrb, Kitl, Myc, and S100 were confirmed via qRT-PCR. Notably, Kitl and MAPKAPK3 emerged as candidate genes for miR-5110-regulated melanogenesis, offering new insights into pigmentation processes.
research Activity evaluation of epidermo-melanin unit and dermal damage in melasma
Melasma results from changes in the skin's pigment and structure, not just pigment cell growth.
research Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin
Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
research Integrating Single-Cell and Spatial Transcriptomics of Human Hair Follicles to Define Transcriptional Signature of Follicular Dermal Papilla
The research identified specific genes that are active in the cells crucial for hair growth.
Community Join
0 / 0 results — no results