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Glossary Diterpenes

chemical compounds with 20 carbon atoms from four isoprene units

Diterpenes are a type of chemical compound made up of four isoprene units, resulting in a structure with 20 carbon atoms. They are found in various plants and are known for their diverse biological activities, including anti-inflammatory and antimicrobial properties. Diterpenes play a role in plant defense mechanisms and have potential therapeutic applications in medicine.

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research Ent-kaurane-type diterpenoids from Isodonis Herba activate human hair follicle dermal papilla cells proliferation via the Akt/GSK-3β/β-catenin transduction pathway

10 citations , January 2021 in “Journal of Natural Medicines”

Ent-kaurane-type diterpenoids from Isodonis Herba may promote hair growth by boosting cell proliferation.

research PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function

9 citations , June 2021 in “Journal of Inflammation Research”

This study found that Euph E and Euri A showed strong anti-inflammatory activity and modulated cytokine and immune functions in macrophages, related to specific signaling pathways.

research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model

April 2017 in “Journal of Investigative Dermatology”

This study found that a single dose of TRP significantly reduced the number of UV-B-induced actinic keratosis lesions in a mouse model and was associated with improved skin histology and minimal side effects.

Platycladus Orientalis Leaves: A Systematic Review on Botany, Phytochemistry, and Pharmacology

research Platycladus orientalis Leaves: A Systemic Review on Botany, Phytochemistry and Pharmacology

24 citations , January 2014 in “The American Journal of Chinese Medicine”

This review compiles data on Platycladus orientalis leaves, noting their diverse pharmacological activities and advocating for more research to clarify their traditional blood-cooling and hematostatic uses.

research Chemistry, biological activities and toxic effects of alkaloidal constituents of genus Delphinium - A mini review

11 citations , October 2021 in “Journal of Herbmed Pharmacology”

This review examines the therapeutic benefits, chemical composition, and medicinal uses of Delphinium species, along with their toxic effects; it reports no new clinical results.

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