2 citations
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January 2006 in “Durham e-Theses (Durham University)” This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.
21 citations
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September 2011 in “Journal of Pharmaceutical Sciences” This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.
21 citations
,
October 2009 in “European Journal of Pharmaceutical Sciences” This study found that drying finasteride solvates at 85 °C for one day produced a metastable anhydrous form.
15 citations
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May 2009 in “Chemical Physics Letters” This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.
61 citations
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April 2007 in “Journal of Pharmaceutical Sciences” This study reported new crystallographic structures and polymorphs of finasteride, including several solvates with distinct X-ray diffraction patterns and thermally characterized properties.