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A Novel Approach Against Male Pattern Hair Loss With Topical Dimethylglycine Sodium Salt (DMG-Na) and Caffeine: Efficacy of a 24-Week, Double-Blind, Randomized, Placebo-Controlled Trial

research A Novel Approach Against Male Pattern Hair Loss With Topical Dimethylglycine Sodium Salt (DMG-Na) and Caffeine: Efficacy of a 24-Week, Double-Blind, Randomized, Placebo-Controlled Trial

August 2025 in “Journal of Cosmetic Dermatology”

The shampoo with DMG-Na and caffeine effectively reduces hair loss and improves hair density in men.

research Topically Applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release

May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology”

Applying DMG-Na to the skin increases blood flow and may help with skin conditions.

N,N-Dimethylglycine Sodium Salt Exerts Anti-Inflammatory Effects in Dermatitis Models and Activates Human Epidermal Keratinocytes

research N,N-Dimethylglycine Sodium Salt Exerts Anti-Inflammatory Effects in Dermatitis Models and Activates Human Epidermal Keratinocytes

July 2023 in “International Journal of Molecular Sciences”

N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.

research Boosting Skin Microcirculation for Androgenetic Alopecia: Does It Work?

February 2025 in “Journal of Investigative Dermatology”

DMG-Na may help reduce hair loss and improve hair growth, but more research is needed.

research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria

29 citations, December 2017 in “Molecular therapy”

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

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community Caffeine + Dimethylglycine (DMG) Shampoo research

in Research/Science 6 upvotes 1 year ago

A user discusses the potential of caffeine and DMG in shampoo for treating hair loss, citing a pending patent and personal plans to test it. They find it more convenient than using minoxidil, tretinoin, and microneedling.