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research The structure of the cornified claw sheath in the domesticated cat (Felis catus): implications for the claw‐shedding mechanism and the evolution of cornified digital end organs

45 citations , April 2009 in “Journal of anatomy”

This study examined the complex morphology of the cornified claw sheath in domesticated cats, uncovering structures and growth patterns that help maintain sharp claw tips essential for climbing and prey capture.

research Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch

5 citations , March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that Piezo2 channels are primarily located on sensory axon membranes in mechanosensory end organs, supporting a model where mechanical stimuli activate Aβ RA-LTMR neurons via axon protrusions.

Hair Bundle Defects and Loss of Function in the Vestibular End Organs of Mice Lacking the Receptor-Like Inositol Lipid Phosphatase PTPRQ

research Hair Bundle Defects and Loss of Function in the Vestibular End Organs of Mice Lacking the Receptor-Like Inositol Lipid Phosphatase PTPRQ

44 citations , February 2012 in “The journal of neuroscience/The Journal of neuroscience”

This study observed that Ptprq mutant mice exhibit significant abnormalities in hair bundle structure and vestibular dysfunction, suggesting similar issues may contribute to hearing loss and vestibular problems in humans with PTPRQ mutations.

research Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia

7 citations , March 2022 in “The FASEB journal”

This study observed that mice with a whole-body deficiency of Cystathionine-β-synthase developed severe hyperhomocysteinemia and related mild symptoms without increased mortality, indicating HHCy may not directly cause end organ damage.

research A review on polyherbal and supplemental approach to treat Polycystic Ovarian Syndrome

December 2023 in “Research in pharmacy”

This review underscores the importance of phytotherapeutic compounds and adjuncts in managing polycystic ovarian syndrome but does not present new clinical evidence.

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community The end of minoxidil and fin/dut regime

106 upvotes 6 months ago

New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.

community My transplant review - for anyone who wants to know how it works

8 upvotes 1 month ago

A user shared their experience with a hair transplant at Estenova in Istanbul, highlighting the painful injection process but overall satisfaction with the results. They also discussed the importance of using topical treatments and the potential for natural hair loss due to DHT, while other users shared their experiences with PRP and ongoing maintenance with finasteride and minoxidil.

community Bought a digital microscope and found some trichoscopic anomalies

29 upvotes 1 day ago

A user noticed irregularities on their scalp using a digital microscope and suspects scarring alopecia, despite using minoxidil and finasteride. Other users suggest seborrheic dermatitis as a possible cause and recommend treatments like ketoconazole shampoo, sulfur soap, selenium sulfide shampoo, and apple cider vinegar rinses.

community Oral Fin+Min: Digital microscope scalp review - Day 0 Vs 3 Months

1399 upvotes 1 year ago

A user used oral finasteride and minoxidil for hair loss, seeing new hair growth under a microscope but no visible change. Commenters debated if the growth was real hair or fibers, and the user will update every 90 days.

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Clinics

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Hair Loss Treatments
Al-Huqail Digital Medical Specialty CenterDammam · SA

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