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research Evaluation of Defensive Responses Associated with Panic in Female Rats: Serotonergic Activation Profile in the Dorsal Raphe Nucleus and Periaqueductal Gray

June 2023

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

research Ovarian Sex Steroid Receptors and Sex Hormones in Androgenized Rats

13 citations , August 2016 in “Reproduction”

High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.

research Endocrine Profile of the VCD-Induced Perimenopausal Model Rat

21 citations , December 2019 in “PloS one”

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

research Activation of Extrasynaptic δ-GABAA Receptors Globally or Within the Posterior VTA Has Estrous-Dependent Effects on Alcohol Consumption and Estrous-Independent Effects on Locomotion

14 citations , September 2017 in “Hormones and behavior”

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer

9 citations , May 2019 in “Experimental Cell Research”

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

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Community Join

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community Do you guys believe oral minoxidil causes faster aging of the face? (By mechanism like bloating, dark circles, and inhibition of collagen)

in Minoxidil 44 upvotes 1 year ago

Oral minoxidil may cause facial bloating and dark circles, making some users feel they look older. Some consider reducing the dosage or switching treatments due to these side effects.

community Listen to your dermat and not reddit posts

in Minoxidil 24 upvotes 1 year ago

Oral minoxidil and vitamins reduced shedding for one user. Others distrust dermatologists and prefer personal research on treatments like finasteride and microneedling.

community Am I balding? Should I just shave it off?(M86)

in Satire 116 upvotes 1 year ago

A user humorously questions if they should shave their head due to hair loss, mentioning Ronald Reagan's impressive hair genetics. Replies include jokes and comments about jealousy and distrust towards older individuals with full heads of hair.

community I don’t believe that Pyri doesn’t go systemic.

in Research/Science 8 upvotes 2 years ago

User experienced hair thickening with pyri but also side effects like reduced sex drive. Stopping pyri and returning to CB restored sex drive, suggesting pyri may go systemic or be incorrectly formulated.

community What do you think about pyrilutamide?

in Product 5 upvotes 1 year ago

Pyrilutamide is being discussed as a potential hair loss treatment, but opinions are mixed, with some users skeptical about its effectiveness and the company's credibility. Some users report combining pyrilutamide with other treatments like dutasteride and microneedling, noting improvements, while others remain doubtful.

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