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research Evaluation of Defensive Responses Associated with Panic in Female Rats: Serotonergic Activation Profile in the Dorsal Raphe Nucleus and Periaqueductal Gray

June 2023

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity

65 citations, October 2008 in “Journal of Neuroendocrinology”

research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer

9 citations, May 2019 in “Experimental Cell Research”

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

research Effects of Flutamide, a Pure Antiandrogen, on Endocrine Parameters in the Adult Female Rat

8 citations, January 1987 in “Gynecological Endocrinology”

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones

197 citations, January 2019 in “Neuropsychopharmacology”

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

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Community Join

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community Listen to your dermat and not reddit posts

in Minoxidil 25 upvotes 3 months ago

Oral minoxidil and vitamins reduced shedding for one user. Others distrust dermatologists and prefer personal research on treatments like finasteride and microneedling.

community Am I balding? Should I just shave it off?(M86)

in Satire 116 upvotes 10 months ago

A user humorously questions if they should shave their head due to hair loss, mentioning Ronald Reagan's impressive hair genetics. Replies include jokes and comments about jealousy and distrust towards older individuals with full heads of hair.

community I don’t believe that Pyri doesn’t go systemic.

in Research/Science 8 upvotes 1 year ago

User experienced hair thickening with pyri but also side effects like reduced sex drive. Stopping pyri and returning to CB restored sex drive, suggesting pyri may go systemic or be incorrectly formulated.

community What do you think about pyrilutamide?

in Product 5 upvotes 3 months ago

Pyrilutamide is being discussed as a potential hair loss treatment, but opinions are mixed, with some users skeptical about its effectiveness and the company's credibility. Some users report combining pyrilutamide with other treatments like dutasteride and microneedling, noting improvements, while others remain doubtful.

community Why is there more skepticism in RU than Pyrilutamide?

in Chat 12 upvotes 2 years ago

The conversation is about skepticism towards the hair loss treatments RU58841 and Pyrilutamide, with users discussing the lack of human testing for RU58841 and the ongoing trials for Pyrilutamide. Some users believe RU58841 has more anecdotal success, while others highlight Pyrilutamide's current research progress.

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