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research Evaluation of Defensive Responses Associated with Panic in Female Rats: Serotonergic Activation Profile in the Dorsal Raphe Nucleus and Periaqueductal Gray

June 2023

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity

65 citations, October 2008 in “Journal of Neuroendocrinology”

research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer

9 citations, May 2019 in “Experimental Cell Research”

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

research Effects of Flutamide, a Pure Antiandrogen, on Endocrine Parameters in the Adult Female Rat

8 citations, January 1987 in “Gynecological Endocrinology”

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones

197 citations, January 2019 in “Neuropsychopharmacology”

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

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Community Join

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community Am I balding? Should I just shave it off?(M86)

in Satire 116 upvotes 6 months ago

A user humorously questions if they should shave their head due to hair loss, mentioning Ronald Reagan's impressive hair genetics. Replies include jokes and comments about jealousy and distrust towards older individuals with full heads of hair.

community I don’t believe that Pyri doesn’t go systemic.

in Research/Science 8 upvotes 1 year ago

User experienced hair thickening with pyri but also side effects like reduced sex drive. Stopping pyri and returning to CB restored sex drive, suggesting pyri may go systemic or be incorrectly formulated.

community Why is there more skepticism in RU than Pyrilutamide?

in Chat 12 upvotes 1 year ago

The conversation is about skepticism towards the hair loss treatments RU58841 and Pyrilutamide, with users discussing the lack of human testing for RU58841 and the ongoing trials for Pyrilutamide. Some users believe RU58841 has more anecdotal success, while others highlight Pyrilutamide's current research progress.

community Is Topical Fin a Reasonable Alternative?

in Finasteride/Dutasteride 5 upvotes 3 years ago

A user discusses mild/moderate hair loss and considers switching from oral to topical finasteride due to past endocrine issues. They seek feedback on topical finasteride's effectiveness and reputable sources, with replies suggesting Minoxidilmax products as effective alternatives.

community People's ignorance on MPB is both frustrating and harmful to balding men and it's important to educate other balding men on Fin/Min/Dut (Discussion)

in Finasteride/Dutasteride 150 upvotes 2 weeks ago

Many are unaware of effective male pattern baldness treatments like finasteride and minoxidil, often opting for ineffective remedies. Educating others on proven treatments and potential side effects is crucial.

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