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research Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing

13 citations , February 2023 in “Aging”

This study found that exosomes from hair follicle mesenchymal stem cells overexpressing lncRNA H19 promoted diabetic skin wound healing by enhancing cell proliferation, migration, and reducing pyroptosis.

research The contribution of probiotics to combined cellular therapy in skin wound healing in diabetic rats

1 citations , October 2025 in “Ulusal travma dergisi”

In this animal study, combined cellular therapy significantly improved diabetic wound healing, and probiotics further enhanced these effects by reducing oxidative stress, apoptosis, and inflammation while promoting vascularization and collagen organization.

Tendon Decellularized Extracellular Matrix Composited with Chitosan with Loading Skin Precursor Stem Cell Exosome for Enhanced Diabetic Wound Healing

research Tendon dECM Composited with Chitosan with Loading Skin Precursor Stem Cell Exosome for Enhanced Diabetic Wound Healing

April 2026 in “Gels”

In this study, exosome-loaded hydrogels derived from skin precursor cells significantly improved wound healing in diabetic rats by enhancing angiogenesis, reducing inflammation, and promoting tissue repair.

research Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair

19 citations , August 2023 in “Experimental & Molecular Medicine”

This study found that the CXXC5 protein is overexpressed in diabetic foot ulcer tissues, suppressing wound healing, and that the small molecule KY19334 accelerated healing in diabetic mice by activating the Wnt/β-catenin pathway.

research Development and evaluation of a fish skin-derived acellular dermal matrix for diabetic wound healing: In vitro and in vivo assessment

January 2026 in “Journal of Biomaterials Applications”

This study found that a fish skin-derived acellular dermal matrix improved wound healing in diabetic rats, showing faster closure rates and enhanced tissue regeneration compared to commercial alternatives.

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community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 1 year ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community Scientists May Have Accidentally Found a Way to Reverse Hair Loss Without Drugs

877 upvotes 1 year ago

2-deoxy-D-ribose is being explored as a hair loss treatment but is not proven effective in humans and may be costly and inconvenient. Minoxidil remains the most effective treatment.

community DHT Blocker without Selenium and Zinc??

5 upvotes 1 year ago

A female user is seeking a DHT blocker without Selenium or Zinc due to hair breakage and is currently using Saw Palmetto, Nature's Bounty Hair, Skin and Nails, Pumpkin seed oil, Dermastamp, and Pura D'or products. She has tried Minoxidil without success and is considering Finasteride but prefers natural options first.

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Noelle Skin
Nice, France

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