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Research

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research Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)

4025 citations , December 2003 in “Human Reproduction”

This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.

research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

1265 citations , October 2013 in “The Journal of Clinical Endocrinology and Metabolism”

This guideline from the Endocrine Society recommends using the Rotterdam criteria for diagnosing polycystic ovary syndrome and outlines first-line treatments, emphasizing hormonal contraceptives and lifestyle intervention.

research Distinct fibroblast lineages determine dermal architecture in skin development and repair

1235 citations , December 2013 in “Nature”

This study found that skin fibroblasts in mice arise from two distinct lineages which contribute differently to dermal structure and repair, impacting hair follicle formation during wound healing.

research Distinct stem cells contribute to mammary gland development and maintenance

721 citations , October 2011 in “Nature”

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

research Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

665 citations , April 2016 in “Nature communications”

This study shows that inhibiting anti-apoptotic proteins BCL-W and BCL-XL can specifically induce apoptosis in senescent cells, suggesting a potential strategy for treating age-related pathologies.

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Community Join

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community Diet changes w Alopecia areata.

5 upvotes 2 days ago

The conversation discusses alopecia areata and whether diet changes can resolve it. One user mentions that their condition fluctuates without dietary changes, suggesting stress as a possible factor.

community diffuse thinning is so much worse than recession

14 upvotes 6 days ago

The conversation discusses hair loss treatments, specifically using 2.5mg dutasteride, minoxidil, and sometimes RU58841, with a focus on diffuse thinning versus recession. It also touches on the impact of estrogen levels on hair density.

community Did changing Dutasteride or Finasteride doses make a difference?

4 upvotes 2 weeks ago

The conversation discusses experiences with changing doses of Dutasteride or Finasteride for hair loss treatment. Users share insights on dosage adjustments and the effectiveness of these medications.

community Difference between two pics is 3 months and 1 week, is this progress?

4 upvotes 2 weeks ago

The user has been using a regimen of 1mg finasteride daily, minoxidil foam 5% twice a day, and recently added oral Dutasteride 0.5 mg once a week, showing noticeable progress in hair growth over 3 months and 1 week. The feedback is positive, encouraging consistency and patience for continued improvement.

community Diffuse thinner, would I respond well to a hair transplant?

29 upvotes 3 weeks ago

The user is experiencing diffuse thinning and has started taking 0.5mg dutasteride and 5mg oral minoxidil daily, planning to wait a year before considering a hair transplant. They are advised to be patient, consult with doctors, and see how the medication affects their hair density before proceeding with surgery.

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Learn

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learn Dihydroquercetin-glucoside

learn Disodium Laureth Sulfosuccinate

learn Diazolidinyl Urea

learn Dimetilsulfóxido

learn Dioscorea Villosa Root

learn Omega 3

Did you know omega-3 can lower scalp inflammation that leads to sudden hair loss? Omega-3 can reduce scalp inflammation, potentially preventing sudden hair loss.

learn PP405

Did you know PP405 peptides can help protect your follicles from DHT? PP405 is not a peptide and does not block DHT: it is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier, aimed at waking dormant follicles. Its registered Phase 2 trial (NCT06393452) measured safety and tolerability in 78 adults with pattern hair loss; it is not approved and not for sale.

learn Hair Transplant

Can a diabetic patient undergo a hair transplant? Diabetic patients can have hair transplants if their condition is well-controlled.

learn Nanoxidil

Key Differences between minoxidil and nanoxidil? Nanoxidil has a lower molecular weight than minoxidil, enhancing absorption and reducing side effects.