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research Studies on Neurosteroids XXV: Influence of a 5α-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism

61 citations, September 2008 in “Biological & Pharmaceutical Bulletin”

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Sexually Dimorphic Effect of Progesterone and Its Reduced Metabolites on the Gene Expression of Myelin Proteins in Rat Schwann Cells

research Sexually Dimorphic Effect of Progesterone and Its Reduced Metabolites on the Gene Expression of Myelin Proteins in Rat Schwann Cells

May 2006 in “Frontiers in Neuroendocrinology”

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

Physician Awareness of the Safe Use of Cyproterone Acetate in Europe: A Survey on the Effectiveness of Additional Risk Minimization Measures

research Physician Awareness of the Safe Use of Cyproterone Acetate in Europe: A Survey on the Effectiveness of Additional Risk Minimization Measures

January 2024 in “Pharmaceutical medicine”

Most European physicians know the risks and safe use of Cyproterone acetate, but few remember receiving official safety communications.

research Effect of Finasteride on the Ovulatory Function of Normal Women

4 citations, June 2003 in “Fertility and Sterility”

Finasteride doesn't affect ovulation in normal women.

research Relationships Between Cerebrospinal Fluid GABAergic Neurosteroid Levels and Symptom Severity in Men with PTSD

59 citations, November 2018 in “Psychoneuroendocrinology”

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

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Community Join

5 / 6 results

community safety of and efficiency of anti androgens for women

in Female 6 upvotes 2 years ago

27F with androgenic alopecia since 17 seeks treatment. Tried spironolactone, caused low blood pressure; believes finasteride is safer and wants to try it.

community We are manipulating our hormones, surely it's prudent to track bloodwork ?

in Finasteride/Dutasteride 64 upvotes 7 months ago

The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 8 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Dutasteride causing us to have… girl babies?

in Finasteride/Dutasteride 26 upvotes 1 year ago

User Kylo313 used dutasteride for 20 years and had two daughters, questioning if dutasteride affects the likelihood of having male vs female children. Replies mostly request hairline photos and discuss anecdotal experiences, with some suggesting correlation doesn't imply causation and that gender determination isn't affected by dutasteride.

community Completely defeated after trying so hard with topical finasteride.

in Finasteride/Dutasteride 24 upvotes 1 year ago

A user who has tried multiple treatments for hair loss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.

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