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GlossaryDehydroepiandrosterone Sulfate (DHEA Sulfate)

hormone precursor influencing sex hormones and hair growth

Dehydroepiandrosterone Sulfate (DHEA-S) is a hormone produced primarily by the adrenal glands, and it serves as a precursor to male and female sex hormones, including testosterone and estrogen. It plays a role in the development of secondary sexual characteristics and can influence hair growth and skin health. Elevated or decreased levels of DHEA-S can be indicative of various health conditions, such as adrenal disorders or polycystic ovary syndrome (PCOS).

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research Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone

1 citations, February 2022 in “The Journal of Urology”

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase

68 citations, September 1990 in “Biochemical Pharmacology”

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

research A Randomized Placebo-Controlled Study on the Effects of Pioglitazone on Cortisol Metabolism in Polycystic Ovary Syndrome

24 citations, April 2008 in “Fertility and sterility”

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

research Roles of Steroid Sulfatase in Brain and Other Tissues

22 citations, January 2008 in “Physiological Research”

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

research Adrenocortical Adenoma as a Cause of Hyperandrogenism Syndrome in a Girl: The Path to Diagnosis

September 2024 in “Medicine theory and practice”

A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.

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community AA and Hirsutism but T levels are normal

in Female 8 upvotes 3 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community Have been on treatment for close to two years, need to know if I should continue or take dut

in Progress Pictures 52 upvotes 3 months ago

A 22-year-old male has been using finasteride, topical minoxidil, and oral minoxidil for hair loss but sees minimal improvement and is considering adding dutasteride. Users suggest additional treatments like dermarolling, PRP, and consulting a dermatologist, or considering a hair transplant.

community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

in Progress Pictures 142 upvotes 2 years ago

A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

community Please take a vitamin & hormone test

in Chat 256 upvotes 1 week ago

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

in Treatment 47 upvotes 4 years ago

A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

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