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GlossaryVaniqa (DFMO)

topical cream that slows facial hair growth in women

Vaniqa is a topical cream containing eflornithine hydrochloride, used to reduce unwanted facial hair in women. It works by inhibiting an enzyme involved in hair growth, thereby slowing down the rate of hair production.

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research Biochemical Features of Primary Cells from a Pediatric Patient with a Gain-of-Function ODC1 Genetic Mutation

15 citations, June 2019 in “Biochemical Journal”

A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.

research Bachmann–Bupp Syndrome and Treatment

July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology”

DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.

research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis

67 citations, September 2001 in “American Journal Of Pathology”

Inhibiting ODC can prevent UV-induced skin cancer.

research Expanding the Phenotype: Four New Cases and Hope for Treatment in Bachmann-Bupp Syndrome

11 citations, September 2021 in “American Journal of Medical Genetics Part A”

Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.

research Serendipity in Trichology

4 citations, January 2011 in “International Journal of Trichology”

Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.

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