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GlossaryVaniqa (DFMO)

topical cream that slows facial hair growth in women

Vaniqa is a topical cream containing eflornithine hydrochloride, used to reduce unwanted facial hair in women. It works by inhibiting an enzyme involved in hair growth, thereby slowing down the rate of hair production.

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research Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition

42 citations , February 1996 in “Journal of Investigative Dermatology”

Polyamines, especially spermidine, are essential for hair growth.

research Co-Operation Between Follicular Ornithine Decarboxylase and v-Ha-ras Induces Spontaneous Papillomas and Malignant Conversion in Transgenic Skin

88 citations , August 1998 in “Carcinogenesis”

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

research Expanding the Phenotype: Four New Cases and Hope for Treatment in Bachmann-Bupp Syndrome

11 citations , September 2021 in “American Journal of Medical Genetics Part A”

Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.

research Inhibition of Metastatic Squamous Cell Carcinoma Development in Protein Kinase C Epsilon Transgenic Mice by Alpha-Difluoromethylornithine with Hair Follicle Degeneration and Hair Loss

26 citations , June 2003 in “PubMed”

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

research Serendipity in Trichology

4 citations , January 2011 in “International Journal of Trichology”

Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.

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