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research Incel Identity Development: A Scoping Review of Biopsychosocial Markers

July 2026 in “Deviant Behavior”

This scoping review examined biopsychosocial markers associated with identifying as an involuntary celibate (incel), highlighting physical appearance perceptions, mental health challenges, and social victimization experiences, and suggesting tailored prevention strategies.

research Sox13 is a novel early marker for hair follicle development

6 citations , January 2019 in “Biochemical and Biophysical Research Communications”

This study suggests that Sox13, although dispensable for epidermal development, serves as a marker for early hair follicle development in Sox13-LacZ knock-in mice.

research Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta prostrata (L.) and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities

4 citations , December 2020 in “Natural Product Sciences”

This study identified ten compounds from Eclipta prostrata, with some displaying potent inhibitory effects against α-glucosidase and acetylcholinesterase enzymes.

research 602 Sox13 is a novel marker for hair follicle development and differentiation

September 2019 in “Journal of Investigative Dermatology”

Sox13 is a new marker for early hair follicle development and differentiation.

research NEDD4 Transcript Variant 3 and IGF-1 as Molecular Markers in the Development and Prognosis of Keloids

January 2025 in “The Egyptian Journal of Hospital Medicine”

This study found that keloid patients exhibited significantly higher expression levels of NEDD4-TV3 and IGF-1 genes compared to controls, indicating a potential role of these genes in predicting and understanding keloid formation.

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Community Join

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community Has anyone done research on Absci's AI‑driven antibody platform? Seeking your thoughts!

4 upvotes 1 year ago

A user is interested in Absci's AI-driven antibody platform, ABS-201, for treating androgenetic alopecia, which shows promising preclinical results and potential for hair regrowth and pigmentation restoration. However, concerns are raised about the drug's development timeline and its advantages compared to existing treatments.

community How is this even possible that there is no cure till now

in Technology 155 upvotes 5 months ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

7 upvotes 5 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community US FDA will now default to only one clinical trial for drug applications, will this accelerate the release of PP405 and other drugs in clinical trials?

13 upvotes 7 months ago

The FDA will now require only one clinical trial for drug approval, potentially speeding up the release of hair loss treatments like PP405. Pelage is expected to present full results of PP405 Phase 2a trials and move to Phase III in mid-2026.

community Possible transgenerational effects of finasteride use on male offspring? (STUDY)

in Research/Science 27 upvotes 5 months ago

Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.

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Learn

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learn Pyrilutamide

Experimental topical anti-androgen, also known as KX-826

learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

learn TDM-105795

What should consumers know about the current development stage and availability of TDM-105795 in hair loss products? TDM-105795 is an experimental topical drug that has completed one 16-week Phase 2 trial in 71 men. It is not approved and is not available in any approved hair-loss product.

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