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GlossaryDeoxycorticosterone

steroid hormone regulating salt and water balance in kidneys

Deoxycorticosterone (DOC) is a steroid hormone produced by the adrenal glands. It plays a role in regulating salt and water balance in the body by acting on the kidneys to promote sodium retention and potassium excretion. This hormone is a precursor in the biosynthesis of aldosterone, another key hormone involved in electrolyte and fluid balance.

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research The Endocrine System and Hair Growth in the Rat

28 citations, March 1942 in “Journal of Endocrinology”

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

research The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

27 citations, October 1945 in “Endocrinology”

Synthetic hormone treatment reduces melanin and hair growth in rats.

research Treatment of Hyperandrogenism in Women

8 citations, January 1996 in “Gynecological Endocrinology”

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

research Sexual Hormones in Human Skin

305 citations, February 2007 in “Hormone and metabolic research”

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

research Pharmacological Options for Treatment of Hyperandrogenic Disorders

6 citations, August 2009 in “Mini-reviews in Medicinal Chemistry”

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

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community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 73 upvotes 4 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Kintor’s KX-826 Pyrilutamide!!

in Research/Science 151 upvotes 3 years ago

KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.