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This report describes the first known case of desmoplastic melanoma presenting as localized alopecia, highlighting the tumor's aggressive behavior and recurrence despite multiple interventions.

This report describes two rare cases of desmoplastic melanoma presenting as alopecia neoplastica, highlighting a potential diagnostic pitfall for clinicians examining patients with scar-like alopecia.

This article reviews the epidemiology of desmoplastic melanoma and reports no new clinical findings, emphasizing higher risks in chronically sun-exposed older males.

The authors concluded that antibodies against tyrosinase and gp100 may be effective in diagnosing melanoma, including challenging variants like amelanotic and desmoplastic types, when appropriate antigen retrieval techniques are used.

Sentinel lymph node biopsy is recommended for all types of desmoplastic melanoma due to higher rates of nodal metastasis.