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    GlossaryDermal-Epidermal Junction

    interface where the epidermis connects to the dermis

    The Dermal-Epidermal Junction (DEJ) is a critical area of skin where the outer layer (epidermis) connects to the underlying layer (dermis). This junction plays a vital role in maintaining skin integrity, facilitating nutrient exchange, and supporting cellular communication. It is essential for wound healing and overall skin health, and its degradation can lead to various skin disorders.

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community 9months progress fin/derma pen/minoxidil

      in Progress Pictures  1001 upvotes 4 years ago
      A user's 9 month progress using Finasteride, Derma Pen/Roller and Minoxidil to treat hair loss. Replies in the conversation include advice on topical application of Minoxidil and Dutasteride for regrowth and hair thickness.