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research Dermal Changes in Osteoporosis Following Prolonged Treatment with Human Growth Hormone

9 citations , October 1976 in “Journal of Cutaneous Pathology”

This study observed that human growth hormone treatment in osteoporosis patients appeared to improve skin thickness and restore dermal structures towards normal without stimulating hair, sebum, or melanin.

research 1447 Anti-senescence effect of extracellular vesicle from hyaluronic acid primed induced mesenchymal stem cells on aged human dermal fibroblast

April 2023 in “Journal of Investigative Dermatology”

HA-iMSC-EVs can improve skin aging by boosting cell growth and restoring collagen and elastin.

research Derma rollers in therapy: the transition from cosmetics to transdermal drug delivery

19 citations , October 2020 in “Biomedical Microdevices”

This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.

research Dermal fibrosis in male pattern hair loss: a suggestive implication of mast cells

19 citations , February 2008 in “Archives of Dermatological Research”

This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.

Single-Cell RNA Sequencing and Proteomic Analysis of Dermal Fibroblasts Cultured From Female Scalp Identifies Significant Alterations in Cell Populations With Age

research O21 Single-cell RNA sequencing and proteomic analysis of dermal fibroblasts cultured from female scalp identifies significant alterations in cell populations with age

July 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

This study investigated age-related changes in female scalp dermal fibroblasts, finding alterations in gene and protein expressions associated with fibrosis and senescence, which could potentially affect hair follicle health and contribute to aging-related hair changes.

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community 3 months on minoxidil / derma rolling. Both pictures immediately after shower

in Progress Pictures 389 upvotes 3 years ago

User had good results with minoxidil and derma rolling for hair loss in 3 months. Others suggest adding finasteride to maintain progress.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

32 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community Microneedling + Min 2 months progress

1064 upvotes 3 years ago

The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.

community M40 - 3 Months progress on Fin/Min

1440 upvotes 9 months ago

A user reported significant hair regrowth after 3 months using 1mg oral finasteride, 1ml 5% topical minoxidil, and microneedling, along with biotin, vitamin D, iron, and zinc supplements. They are optimistic about continued progress despite initial skepticism.

community Holy shit. Verteporfin may actually be the cure

1013 upvotes 2 years ago

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

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learn Beta Polypeptide

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