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research Topical retinoids: role and place in acne therapy

March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï”

This source highlights that topical retinoids, particularly adapalene and its combinations, are crucial in treating acne due to their rapid action, sustained effects, and good tolerability; the study underscores the enhanced patient adherence with Deriva C MS gel for acne treatment.

research Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis

19 citations , March 2018 in “Journal of Investigative Dermatology”

This study indicates that transient Msx2 expression is critical for wound-induced hair follicle neogenesis, with distinct phases in the healing process essential for epidermal competence and hair regeneration.

research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles

18 citations , January 2008 in “Journal of The American Academy of Dermatology”

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

research Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture

23 citations , November 2015 in “Phytotherapy Research”

This study found that cucurbitacin I from bitter melon most effectively inhibited the growth of lung cancer cells and promoted hair cell growth in cell cultures.

research Chemical profiling and quantitation of bioactive compounds in Platycladi Cacumen by UPLC-Q-TOF-MS/MS and UPLC-DAD

47 citations , March 2018 in “Journal of Pharmaceutical and Biomedical Analysis”

This study identified 43 compounds in Platycladi Cacumen, including flavonoids, and found significant chemical variation in flavonoid content across different regions and processed products.

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community Verteporfin and Microneedling

in Treatments 2 years ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

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